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Healthcare Provider FAQs

How to Prescribe

How do I prescribe Plenity?

Where is Plenity in my e-prescribing platform?

How do I get Plenity added to my prescribing platform?

Can I send Plenity prescriptions to a local retail pharmacy?

What should I do if I already sent a patient's Plenity prescription to any pharmacy other than GoGoMeds Pharmacy?

Before prescribing Plenity, are there dosage requirements and clinical imperatives I must explain to patients?

How much does Plenity cost?

Is Plenity covered by insurance?

How long will it take for my patient to receive their first order once prescribed through GoGoMeds Pharmacy?

If I refer a patient to Plenity Telehealth by Ro, will I have access to my patient’s records?

If I refer a patient to Plenity Telehealth by Ro, how long will it take my patient to get Plenity?

Can I prescribe for specific patients who require my oversight and refer others to Plenity Telehealth by Ro?

Will Ro reach out to my patient regarding any other matters related to their health?

More About Plenity

What is Plenity?

How does Plenity work?

Did Plenity work in clinical trials?

Is Plenity a drug?

What are the side effects of Plenity?

How safe is Plenity?

Who can take Plenity?

Is Plenity suitable for children?

Is Plenity kosher or vegetarian?

Is Plenity wheat- and gluten-free?

Ready to prescribe?

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Intended Use

Plenity® is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 25–40 kg/m², when used in conjunction with diet and exercise.


Important Safety Information

  • Plenity is contraindicated in patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide
  • Plenity may alter the absorption of medications. Read Sections 6 and 8.3 of the Instructions for Use carefully
  • Avoid use in patients with: esophageal anatomic anomalies, including webs, diverticuli, and rings; suspected strictures (such as patients with Crohn’s disease); and complications from prior gastrointestinal (GI) surgery that could affect GI transit and motility
  • Use with caution in patients with active gastrointestinal conditions such as gastro-esophageal reflux disease (GERD), ulcers, or heartburn
  • The overall incidence of AEs in the Plenity group was no different than the placebo group
  • The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence

Rx Only. For the safe and proper use of Plenity, refer to the Healthcare Professionals Instructions for Use.

  1. Plenity [Instructions for Use]. Boston, MA: Gelesis, Inc.; 2021.
  2. Greenway FL, Aronne LJ, RabenA, et al. A randomized, double-blind, placebo-controlled study of Gelesis100: a novel nonsystemicoral hydrogel for weight loss. Obesity. 2019;27(2):205–216.

BMI=body mass index; GI=gastrointestinal; HCP=healthcare provider; HIPAA=Health Insurance Portability and Accountability Act; GLOW=Gelesis Loss Of Weight.